求人帮忙挂YY积分,ID66273876 满100贡献送yy月票有什么用。

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黄琳,徐想娥,汪万强
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作者(Author): 黄琳,徐想娥,汪万强
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本文作者相关文章Thyroid Hormone and Lactation in the Rat.
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Medicine, Research & Experimental 57 out of 124 |
Medicine, Research & Experimental 55 out of 124
2016 Release of Journal Citation Reports, Source: 2015 Web of Science Data
Dept. of Dairy Husbandry, University of Missouri, Columbia
We have investigated effects of l-thyroxine alone, and in combination with oxytocin and growth hormone (GH) upon lactation
in the rat. Amount of milk obtained by a litter of 6 during 30 minutes nursing on day 14 postpartum, expressed as percent
litter body weight, was used as the index of response.
1. 3.0 μg/100 g/day l-thyroxine, a level equal to the highest daily thyroid secretion rate previously observed, injected daily
from days 7–13, increased average milk yield 37%. That obtained with aid of oxytocin, to insure maximum milk removal, in rats
injected for 7 days with l-thyroxine alone, or with 1 mg GH/day, was increased 63.2 and 73.7%, respectively. With addition
of each hormone there resulted also a progressive reduction in variation among individual milk yields. It is suggested suboptimal
thyroid hormone secretion may limit intensity of milk secretion in many lactating rats. 2. Increased milk secretion, obtained
with l-thyroxine with or without GH was not reflected in significant increases in litter growth as analyzed by percent weight
gain during period of treatment. Thyroxine had no adverse effect on maternal body weight. Increase in maternal weight due
to GH was offset by simultaneous treatment with thyroxine. 3. Thyroxine induced a significant increase in maternal pituitary
gland weight which was offset when administered with GH. Adrenal gland weight was significantly increased in lactating rats
injected with l-thyroxine plus GH but was unaffected by l-thyroxine alone.
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