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OBJECTIVES: To examine whether intermittent oral 1 alpha(OH)D3 treatment of patients on haemodialysis with secondary hyperparathyroidism (HPT) was able to maintain the marked suppression of PTH, which previously had been induced by an intermittent intravenous administration of 1 alpha(OH)D3. Simultaneously, the effect of the different routes of administration of 1 alpha(OH)D3 on the circulating nike Air Max 90 Nz levels of N- and C-terminal PTH fragments was measured.DESIGN: An open study of patients on chronic haemodialysis.SETTING: Renal division, Rigshospitalet, Copenhagen, Denmark.SUBJECTS: A total of 26 patients started and five patients completed the total protocol.INTERVENTIONS: The treatment protocol was divided into three parts: (i) 1 alpha(OH)D3 administered intravenously for & 300 then (ii) 1 alpha(OH)D3 administered orally for 100 days, followed by (iii) 1 alpha(OH)D3 administered intravenously again for another 100 days. 1 alpha(OH)D3 was given three times a week at the end of each dialysis.MAIN OUTCOME MEASURES: Intact PTH, N- and C-terminal PTH.RESULTS: Intact PTH levels were significantly (P & 0.0001) suppressed by 90.4 +/- 3.3% after 56 days of intermittent intravenous 1 alpha(OH)D3 treatment.
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To understand the mechanisms responsible for this homeostasis, we address the following issues: (i) Can firing rates of single cells be modified? (ii) Once modified, what mechanism(s) can maintain the changes? We show that firing rates of hippocampal pyramidal cells can be altered in a novel environment and by Hebbian pairing of physiological nike Air Max 90 input patterns with postsynaptic burst discharge. We also illustrate a competition between single spikes and the occurrence of spike bursts. Since spike-inducing (suprathreshold) inputs decrease the ability of strong (\'teaching\') inputs to induce a burst discharge, we propose that the single spike versus burst competition presents a homeostatic regulatory mechanism to maintain synaptic strength and, consequently, firing rate in pyramidal cells..
The impact of the independent variables on parasite prevalence was investigated with bivariable and multivariable analyses. The prevalence of Giardia (12%) was influenced by age and community of residence. The prevalence of Entamoeba (10%) did not significantly vary by the independent variables.(Priciple)
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为了保障您的权益，请购买前务必咨询其是否接受的鉴定，如果他挂羊头卖狗肉，可以用聊天记录作为证据，祝购物愉快！
为了保障您的权益，请购买前务必咨询其是否接受的鉴定，如果他挂羊头卖狗肉，可以用聊天记录作为证据，祝购物愉快！
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为了保障您的权益，请购买前务必咨询其是否接受的鉴定，如果他挂羊头卖狗肉，可以用聊天记录作为证据，祝购物愉快！
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